Masticatory Muscle Myositis

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What It Is

Masticatory muscle myositis (MMM) is a neuromuscular disease in which the muscles used by the dog to chew – the jaw and temporal muscles, which are called masticatory muscles – are inflamed, and it is painful and difficult or impossible for the dog to open its mouth.

MMM is an immune-mediated disease which is reportedly well known in the Cavalier King Charles spaniel as being hereditary. Other breeds in which MMM is most common are German shepherds, Labrador retrievers, Doberman pinschers, and Golden Retrievers.

“Myositis” is a general term for inflammation of the muscles. “Immune-mediated” diseases are conditions in which the immune system may over-react or start attacking the body. MMM has also been known as “eosinophilic myositis” or “atrophic myositis”. The inability to open the mouth is called “trismus”.

This condition is limited to the masticatory muscles because they have a molecular structure, called 2M muscle fibers, which are found nowhere else in the dog’s body. Masticatory myositis results when the immune system’s antibodies specifically target these 2M muscle fibers.

The disorder is known to have an early onset in Cavalier King Charles spaniels, having occurred in Cavalier litter mates as young as twelve weeks of age, and several other CKCSs before six months. The reported typical age of onset is about three years

In a 2005 study, Dr. Diane Shelton, board certified in veterinary internal medicine, concluded:

“In a search of the database of the Comparative Neuromuscular Laboratory over the years 2001-2005, masticatory muscle myositis was confirmed in 11 young Cavalier King Charles Spaniels with onset at less than 6 months of age. In several cases, onset followed within 10 days of vaccinations. Although long-term information is not yet complete, there was resolution of clinical signs of masticatory muscle myositis in most cases. Of interest, other complications such as early onset hypothyroidism and allergies were reported. Additional information will be provided as more is learned about this early-onset masticatory muscle myositis in this breed.”


Masticatory muscle myositis may start suddenly or appear gradually. The main clinical sign is difficulty in opening the mouth (called “trismus”). In the initial (acute) stage, there may also be swelling of the jaw and temporal muscles, pain in the jaw, and bulging eyes due to the swollen muscles behind them. There may be a fever and a swollen local lymph node. The dog will seem to in pain when he tries to open his mouth or attempts to chew and will be reluctant to eat.

If MMM is not noticed early enough, it develops into the chronic stage, in which damaged muscle fibers are replaced with fibrotic connective tissue which results in further restriction of opening the mouth. In the chronic stage, there is noticeable atrophy of the masticatory muscles and inability to open the mouth due to the fibrosis. Instead of appearing swollen, the dog’s jaw and temple muscles will hollow. The fibrosis can become so severe that the mouth can not be opened even under general anesthesia.– a very serious form of lockjaw. Unfortunately, many owners do not recognize that their dogs are having a problem until they reach the chronic phase.


You may expect your Cavalier to endure a battery of diagnostic tests, including complete physical and neurologic examinations, general and specialized blood tests – there is a unique blood test for masticatory muscle myositis called the “2M antibody” test – as well as a muscle biopsy, x-rays, urinalysis, and electromyography.

The Most Accurate Blood Test for MMM

The 2M antibody blood test detects circulating antibodies against masticatory muscles’ 2M fibers. Only the masticatory muscles have the molecular structure called 2M fibers. Masticatory myositis results when the immune system’s antibodies specifically target these 2M fibers.

The 2M antibody test is an “immunocytochemical” test, in which positives for MMM reportedly have been proven to be 100% accurate, and false negatives for MMM have occurred only 10% to 15% of the time.

The test is conducted by the Comparative Neuromuscular Laboratory at the University of California, San Diego. Serum samples should be sent to the laboratory; its turn around time for reporting results is five to seven week days. The laboratory’s director is Dr. G. Diane Shelton, ACVIM board certified in internal medicine. Contact information is on this website: Comparative Neuromuscular Laboratory

The purpose of some of the tests is to rule out other possible causes of the symptoms. For example, the physical and neurologic examinations are to confirm that clinical signs are limited to the masticatory muscles. Polymyositis is a more generalized muscle inflammation of the masticatory muscles and other muscles but otherwise is difficult to distinguish from masticatory myositis. Other possible causes of such symptoms include temporomandibular joint disorders, and endocrine disorders, such as Cushing’s syndrome and hypothyroidism.

General anaesthesia may be called for to get the dog to open its mouth to check for other possible causes of the pain, such as broken teeth or bones or a dislocated jaw. In advanced chronic cases, the dog’s jaws may not open even under anaesthesia.

If the dog’s jaw or temporal muscles have started to atrophy (a symptom in the chronic stage of MMM), the examining veterinarian should find out if the dog has been treated with lengthy (seven days or longer) corticosteroid therapy for another disorder, since corticosteroids have been known to cause these muscles to atrophy.

The owner should tell the veterinarian about any recent vaccinations of the dog. Dr. Diane Shelton, board certified in veterinary internal medicine, recently reported that several young Cavaliers developed MMM within ten days of vaccinations.


It is important to begin therapy of the MMM-affected dog as early as possible, so that the acute stage does not progress to the chronic stage.  However, treatment should not begin before thorough testing and diagnosis.

The standard course of treatment consists of heavy, lengthy doses of corticosteroids, such as prednisone, until the dog’s jaw seems to open normally. Then, the doses may be lowered gradually over six to nine months. If the medication is discontinued too early, the dog may be expected to relapse. So, sufficient dosages of corticosteroids need to be given and for a sufficient period of time. MMM is known to respond well initially to corticosteroid therapy, but a relapse usually will occur if the treatment is discontinued prematurely. In some cases, the drug cannot ever be completely stopped.

Prednisone is a synthetic corticosteroid which serves as an “immunosuppressant” intended to suppress the dog’s immune system. Prednisone may have some harmful side effects. Patients on long term prednisone will drink and urinate excessively. For dogs not able to tolerate the side effects of corticosteroids, another immunosuppressive drug, azathioprine (Azasan, Imuran, Azamun, Imurel) may be prescribed in addition to corticosteroid treatment.

Other drugs which have been considered for treatment of MMM include dexamethasone, which is approximately ten times stronger than prednisone, and cyclosporine, which is another immunosuppressive drug, and colchicine, which is used for its anti-fibrotic properties in liver disease.

The dog may require a semi-liquid diet during initial recovery. Its mouth should not be forced open, but the dog should be encouraged to chew its toys, as a form of physical therapy.


Prognosis of recovery from masticatory muscle myositis is determined by the degree of fibrosis present and the dog’s response to treatment. The prognosis is good if: (a) MMM is detected early, in the initial “acute” stage; and (b) the treatment is appropriate, meaning mainly aggressive immunosuppressive therapy comprised of high doses of medication given long enough to avoid a relapse. “Good” prognosis means that a full or significant partial range of jaw motion is regained.

Dogs which are not treated until they are in the “chronic” stage of masticatory muscle myositis may be expected to have a less favourable prognosis.


60 Responses to Masticatory Muscle Myositis

  1. Ken says:


    I went to my vet today because I noticed that the bone in the rear of my 2-1/2 yr old shepherd’s head seemed to have gotten larger – like a small horn. Something I had not noticed before. I am not sure that it actually changed, but wanted to make sure the bone was not growing due to it seemingly being something I had not noticed previously. My vet said it was not the bone that got bigger, but that the temporal muscles had atrophied and mentioned masticatory muscle myositis. It did not seem to me that the muscles around his temples had atrophied as I think zi would have noticed if his head had gotten at all smaller. And she had never met my dog before so had nothing to compare it to to make such a statement.

    Upon reading your article (and a few others) it seems that the atrophy would be a result of lack of use of the jaws due to pain. Is this correct? If so, then it would seem that this is not the cause of the small “horn” that I feel at the back of my dog’s head. As my dog has had absolutely no issue or pain with eating, chewing or any other activity of the jaw. So it just does not make sense to me that there would be any atrophy of his head muscles if there was absolutely no clinical signs of this disease and his use of the muscles has not changed in any way.

    I am having them do the 2M antibody blood test on Saturday to see if any antibodies are in his system, but my gut tells me this disease is not something that my dog experienced. Can you please let me know if my thoughts relative to the muscle atrophy are correct or not, as, if they are, I want to make sure there is not something else that I should be doing.


    • admin says:

      We now have a Facebook group of the same name where you may get other options. You can cope and paste this question.

      They don’t use the jaw not only to pain but because the muscle is affected and has no strength to bite.

  2. Kristine says:

    My 7 yr old collie was just diagnosed with chronic MMM. Due to another medical condition (MDR1 gene mutation) she cannot tolerate prednisone or he other afore mentioned drugs.
    Do anyone have any ideas?

  3. Doug A. says:

    My baby Sawyer has this terrible disease. I am so glad they make Prednisone, because it works fantastic.
    The only problem is that he wants to eats all the time and drinks a lot of water.
    Does anyone know how safe Prednisone is for taking long-term or life? Is there anything natural or better than Prednisone?

  4. Janet Stafford says:

    My girl, Nikki will be 12 next month and was just diagnosed with MMM last week. Well they are pretty sure. Had the blood test and except for two areas she is extremely healthy but those areas, one in particular, is almost a positive that MMM is what she has. I was one that never saw anything unusual until all of a sudden ONE day, I realized her head had caved in in the left side. I read up on it and it was said to be either a tumor, or something causing the muscle to atrophy. At the time I didn’t have any money to do a thing about it. Then about a month or two later, I noticed that her cheek on that side had caved in toward the inner area, and then noticed how she she wasn’t chewing her dry food or her bones. That’s when I knew something was getting worse. I then DID take her to the vet and now, here we are. Once the blood work showed more pointing to MMM, the vet started her on the prednisone, which in her case, he prescribed 50mg a day. I have been reading about all the side effects, symptoms, and secondary conditions that can happen from long term steriod use, and just wish I knew, without asking my vet himself, if 50 mg a day seems a bit too much. I have read a lot of others info and none come close to this high of a dosage. I hope she wasn’t given too much to take. I also read up on the fact that when on the steroids, the atrophy can get worse at first, but it is not a bad sign, rather a good one that the steroid is working. Nikki is on her 4th day and I have seen that already. it looks more sunken on the head and I see what seems to be the top of a round object which I cannot find on the internet to say if it belongs there, what it is, or if could be a tumor. She has had a seizure disorder all her life since 5 yrs old, but not epileptic. I still wonder if this is all related. She is a beautiful, stunning, perfect mix of Blk Lab, German Shepherd and Husky. Very intelligent, has been prescribed to me as a non-certified service animal, and she is my world! We have been through hell and back together and I know her time is getting shorter anyway, at 12, but she is just so damned healthy if it weren’t for this! I’m so broken up over it.

    • admin says:

      What a sad story, the fits are connected with MMM, I had to give my dog suppositories for it. I honestly can’t remember what dose my baby was on, but i would guess your vet is giving a high dose (if it is high) because the condition is so bad, it sounds severe to me. my thoughts are with you x

  5. ask says:

    Aw, this was a really good post. Taking the time and actual effort to generate a really good article…
    but what can I say… I hesitate a lot and never
    seem to get anything done.

  6. Alyson says:

    My 1 year old cairn terrier was recently diagnosed with MMM. I would strongly caution anyone from trying to diagnose via the internet – this is not a disease to “wait around and see”. Every article written states that it is a disorder primarily in large breed dogs and around 2-3 years of age. My Sadie is a 1 year old, 15 pound cairn terrier. Do not ignore systems no matter what.

    Sadie stopped taking treats on our walks, stopped barking, and stopped playing with her friends at the park. I took her to the vet and they tried to look in her mouth, she would not let them. They sedated her, and under sedation her jaw was locked shut. Xrays showed that her lymph nodes were quite swollen.

    My vet suggested MMM, but neither of us thought that was a likely diagnosis because of it’s tendency in larger breeds. Never the less, he put her on a high dose of pred (2mg/kg), because, quite honestly, as he put it, there aren’t a lot of other diagnoses that would support a locked jaw and swollen lymmph nodes. Her jaw released within about 10 days. I had the antibody test done to confirm, and it came back positive. I was shocked, but also not really.

    She was a zombie on this high dose, but it helped her jaw. She is now finishing off her month at 1mg/kg, and will do a month at .5mg/kg, then .25mg/kg. All in all, her pred treatment will be about 5 months.

    Her jaw is much better now. She’s barking ar squirrels, she chewing her toys, she’s yawning nice and wide, and she’s getting her spirit back.

    My word of warning is this: Do not wait. The disease progresses rapidly and the further the muscle deterioration, the more likely a relapse is.

  7. Natasha says:

    My 5 year old cocker spaniel has been diagnosed with this yesterday, after 11 weeks of Metacam for random lameness of alternating back legs and xrays showing slight artirits in one of his toes his legs are still stiff, he also had an ear infection for almost that whole time and approx 2-3 weeks ago I noticed he seemed stiff when yawning but the vet thought it was due to his ear. Now he is struggling to eat, can’t pick up a ball and is very sad his eyes seem droopy and red too. He can’t start prednisolone until Sun night as he had Metacam yesterday evening, does this sound like acute or chronic? I’m so worried about him, the jaw pain and stiffness has come on almost suddenly and got worse the last week especially few days.

    • admin says:

      I am not a vet so cannot say, but it sounds like classic symptoms for MMM Get him soft food to help him, id recommend you buy it from the vet and not buy these cans of pedigree chum they are just rubbish and have no nutritional value. Hope his symptoms get relief from the new medication. xx hugs.

  8. Trish says:

    I am on the 13 day of treatment for MMM with my GSP. He is eating again and even picked up a tennis ball to retrieve. I wondered if anyone knows if after the months of treatment and the pup getting better will his head return to normal? My dog’s head became boney and narrow which is the opposite of what he had been. With the treatment will some of his muscle reappear and thicken his head shape?

    Thank you. Great info on this site and helped me immediately go to the vet with info.

    • admin says:

      Thanks for the compliment, sadly this site will close soon as i have shut down the business, a lot of years work going to oblivion :( anyway i hope i have helped a few people. as regards your questions unfortunately my dog died before he got better so i don’t know if the head returns to normal. sorry. I know what you are going through and hope it goes well for you. Max used to pick up food with his mouth and just let it fall out that is when we noticed something was wrong ….. it went from bad to worse we were so lucky we had a good vet. best of luck x

    • Aine Mulcahy says:

      Trish, what symptoms did your GSP have? Did you notice any improvements in the first few days?x Áine

      • Trish says:

        The symptoms came on suddenly or I just was unaware. He was whining and would not open his mouth. A normally very active playful dog would not play. He has been on the predisone for 3 and half months now and seems to be better. He is playful and eating. I have lowered the dose slowly. His head changed shape drastically and still is boney and thin…. lost his good looks but I love him anyway.

        • admin says:

          You can’t but love them. Yes the head does change shape and it can be quite alarming and all you can do is love them and give them soft food.

    • Tiffany says:

      My vet informed me most likely once the muscle is lost it will not return.

  9. Aine says:

    I am so afraid my 5 year old rottie has developed this and It’s in the chronic phase. She’s my baby and I can’t lose her! She has developed sunken temples on both sides and as of last night her jaw movement is extremely restricted, up until this there had been no other signs. Rang my vet at 12.30am (saturday) last night to tell them what I feared and was only told you shouldn’t have rang, what did I expect them to do and we’re open on Tuesday! Meanwhile I know my dog and that she’s not right and that if it is the chronic phase you have to act fast.,so I rang another vet who said they’d see me this morning. My dog this morning has now less movement again in her jaw. How expensive is this treatment if it is MMM? She’s not in pain, still her usual beautiful self, but has over the last 3 months developed pimple type spots on her lips and chin, was this the sign my vet missed? I’m so scared, is there any hope? We’re based in Ireland

    • admin says:

      The vet you rang who said you shouldn’t have rung is very unprofessional. Even if there was nothing they could of done they could of put your mind at ease somehow. I’d change vets firstly. I am not a vet only a dog owner who has gone through this with my own dog sadly. Is your dog insured as it is expensive as you need steroids you need pain killers and you need tablets for something else i think its muscle relaxants. this can also evolve into epilepsy so you may need anti convulsive drugs then you need to buy special food as they can’t eat Kibble and you need to buy a good soft food none of this pedigree rubbish. I don’t recall pimples on my dog. What makes you believe this is MMM and in the chronic phase? has she stopped eating and loosing weight? i hope you get some good news about this x I was in Ireland, and unfortunately i will be shutting down this web site soon.

      • Aine Mulcahy says:

        My dogs head has sunken on both temples, cannot pick up her tennis ball as normal but is holding it in her front teeth. she doesnt appear to be in any pain and is eating and drinking. I swapped vets straight away and my old vet will be getting a very nasty phone call as soon as I can stop crying and worrying if my dog is going to be ok. the vet today is pretty confident that it is MMM and has started Belle on a dose of steroids, but her right temple seems to have sunken more this evening. We’re back to the vet again on friday, sooner if I need to. How long does it take until the steroid should start to help the jaw. Thank you for your advice, it’s nice to know your experience with it. I’m sorry to hear you are closing the page, its the only place I have found comfort and simple reading relating to MMM

  10. Michele says:

    Hi I have a two year old (almost) miniature pinscher. Who in february this year developed severe jaw pain and he looked like his glands were swollen at the top of his neck. I took him to the vet and because we couldn’t really open his jaws to have an examination he was just put on metacam for a week. This worked the swelling went down- the pain went away and he became a happy little fellow again. However it was at this stage as the swelling went down, that I noticed that his masticulatory muscles had atrophied. He has never exhibited any pain since last february. I continued vet treatment with him in an attempt to see if we could undo the atrophication and it has come back a little but not fully. He has never been in pain since and the vet has assumed that he has MMM. We started him on pregnisolone in May this year and he bulked up a lot – He was aways a small dog and at times weighed as little as 3.5kg. A healthy weight for his frame would be 4.75 / 5kg. He started to look (no offence intended) but he looked like Arnold Schwartzeneger – i.e he didn’t really look natural, the muscle atrophication did not change. We then neutered him in July this year and we took him off the pregnisoline in preparation for the operation – he was pregnisoline free for 8/9 days pre op and we haven’t as of yet put him back on. However he has never looked as well or been as well in himself since he was neutered. He has lost the bulked up look – he is playing with all the other dogs and is showing no signs at all of pain. He is eating well and chewing bones etc (which i encourage) albeit with little effect. I was just wondering is it possible that he does not have mmm and that this was something else altogether. My vets dont have much experience of mmm. He really is in such great form since he was neutered I was wondering could it have been something else hormonal that could have caused this awful pain and swelling and atrophication that he had. should i restart prenisolone now as he was only on the treatment for about 8/9 weeks. He had started on 20mg per day for first week and was on 15mg per day when we took him off it for the operation.

    • admin says:

      The bulking up was caused because that drug is a steroid. I hadn’t heard of that breed having MMM. But not to say it can’t happen. If your dog is not in pain and is acting ok I would not start him back on the drug. See how he gets on. Best of luck x

      • michele says:

        Thanks. Yes I think I will leave well enough alone and see how he gets on for now.

        • Elaine says:

          Hi. Hope he is still well, I also agree with the admin, to not start him on steroids unless you start seeing an outbreak.. They are not good for them especially long term .
          Good luck it’s a tough battle but worth it for our little ones 😉

  11. Kim says:

    Our 8 year old Brittany, Thursday, was given MMM as a likely diagnosis today. The blood test will go out tonight and we are worried sick. The vet did not want to start steroid therapy before the blood was drawn. Thursday’s only symptom has been a sudden inability to fully open her mouth. She does not seem to be in pain but we giving softer foods just in case. Thank you for all the info provided on this site.

    • Elaine says:

      Hope she is ok now.. Just remember sometimes MMM does not always show up in bloodwork.
      What did they end up finding??

  12. Merran Hamilton says:

    I just stumbled across this info. I have a 4 year old German Sheoherd who was tested for MMM at the end of last year. He visited two specialist vets one who said he had it and made the diagnosis from the dogs presenting clinical signs. Which were muscle atrophy of his left temporal muscle. He didn’t suggest any treatment other than for me to observe. I was concerned about that given what my own research told me about the disease. My dog had no jaw pain. I took him elsewhere and he had blood tests sent to the US, CT scans, and a muscle biopsy. The blood tests came back negative. And the other tests showed nothing remarkable other than the atrophy of his muscle. He was diagnosed with Idiopathic Trigeminal Nerve Neuritis. He seems well but on occasions he pants profusely even when it’s really cold, his skin breaks out, so he’s treated for that and it appears to be immune related, and I feel that his head shape is continuing to change. He had a beautiful large expressive male head, even the GSD people refer to him as a female if they don’t know him. That never happened before because it was so obvious that he was a male because if his head size/shape. I was wondering if anyone else can relate to this and if so did you consider a second round of blood tests because the first came back negative? I don’t know what else to do. He was not put on any treatment for his muscle atrophy because the second specialist believed it was just a once off. I don’t know what to do. Thanks to anyone who can help…. :)?

    • admin says:

      Thanks for your input. I have not heard of MMM affecting GS but then who is to say it doesn’t. The change of head shape is a good indicator something is going on. Do you have before and after photos you can show your vet? Can your dog chew? Does your dog seem to be in pain or discomfort? I’m not a vet or trained in any way I just did a lot of research when my own dog got MMM and I found it so hard to find information I thought I would try to compile something based on both what I found and my out experience. To me the mis shapen head of your dog is a clear sign there is something serious going on. Maybe not MMM but something. I hope you find a solution. We had several blood tests done on Max to prove it was MMM xx

      • Merran says:

        Thanks for the reply… I’m thinking if getting a third opinion. I do have before and after photos. The specialist vet hospital came to the conclusion that he had, had a one off issue which caused his muscle atrophy and that I should not expect any further muscle wasting. The problem is that I think his head is continuing to change shape, nothing dramatic although other people are starting to see what I see. He has had most things discounted, including sheath cancers and thyroid issues. They didn’t test for Toxoplasmosis which can cause muscle atrophy but that was because he did not have any other clinical signs which would indicate it’s presence. I think I will ask for the blood tests to be repeated for MMM. That’s all I can do… If they come back negative a second time… I will have to let it rest.

  13. Jenna says:

    Our boxer was diagnosed with MMM at about 6 months of age. It was very scary, and I felt so helpless. Our vet originally thought she had broken her jaw, but we didn’t know how that would have been possible. We saw a specialist who diagnosed the MMM. She was on steroids for many months, but she got better. Months after starting treatment she was able to pick up her tennis ball again to play. I cried tears of joy the day that happened. :) Anyway, she is 4 years old now and I always watch her closely for any signs of relapse. Everyone going through this should stay positive because your babies can get better!

    • Elaine says:

      So happy she’s on the mend, continue to watch her(for another outbreak) be sure she is keeping her jaw active( tennis balls, sticks, marrow bones etc. :)

  14. Sue says:

    My dog has just been admitted to the vets with suspected mmm! He has been crying in pain trying to open his mouth for only the last 12 hours with no symptoms before that.It is something I have never heard of before so am desperately reading about other peoples experiences

  15. Elaine says:

    Great article. Our 2yr old golden retriever has been diagnosed with MMM, unfortunately. We are able to recognize the early stage when an outbreak is ready to happen, and than start a steroid treatment which usually lasts for about a month. He responds well to them but hate to leave him on them since they can effect the body and temperament negatively. We recently started a liver cleanse and probiotics (both are in a powder form) given by a holistic vet. We are hoping to see positive results within the next few months.
    Any information on how these can help and aid with any outbreaks??

    • admin says:

      Elaine my dog was on the Steroids for months and months at a time and never did we see a change in his temperament. He was always the Same. He was sad though as he couldn’t eat though he would try. So we would soften his food and leave it over night to get really soft so he could almost drink it. He was a good old soul and was always wagging his tail and licking you. I’ve never heard of a holistic vet. They weren’t about in poor Max’s day. I hope it works for you. X

      • Elaine says:

        Thank you for the follow up.. :) we are trying a new treatment or a “remedy” it is in a 100% natural ingredient in form of powder. The vet wants to try it to see if they can keep his immune system up to prevent frequent outbreaks of. MMM. with this.. Here’s hoping!! And keep up the good work/info on this :)

      • Elaine says:

        Also, I look forward to any info you have for sharing. I have a lot of info on this as well, let me know if I can help at all. I am not a vet! but at this point! I have seen a lot and gathered a lot of info on this rare and sad disease. Xo

        • admin says:

          Thank you if you would like to share here about the holistic side I’m sure people would love to read it. thank you for your offer of sharing, that is very kind. x

    • Sue says:

      Can you tell me the signs to look for before an outbreak?

      • admin says:

        Hello Elaine, I am not qualified just a dog owner who has done a lot of research which i have posted here, my own dog Max had this and the first signs we noticed was he was pawing at his mouth and wouldn’t eat he would try but would drop the kibble right out of his mouth, this would be the defining moment i think. He couldnt open his mouth even when you would try to help. another symptom is a stiff neck although our Max didn’t have this. A blood test taken by your vet can confirm or rule out this illness. but it will have to be sent to the states for diagnosis. (or at least in my day this was the case) So there is a lengthly wait for the results sadly. Oh dry eyes also, Max had dry eyes. hope this helps you in some small way.

        • Elaine says:

          Often a blood test will not diagnose this. In fact, Bentley’s came back negative. He has not had an outbreak for 3 months since we started giving him a probiotic powder and a liver cleanse!!
          You can detect an outbreak if your dog likes to hold a tennis ball or stuck, how he eats his food, or even barks. We watch him daily during his activities just to be sure.
          I have never believed that these holistic powders would work, and it could be a strange coincidence but I urge you to look into this if you can
          :) let me know any questions..

    • Sharon says:

      Hi Elaine, my Golden Retriever is 5 years old now but was diagnosed with MMM when he was 1 1/2 years old. Since his initial diagnosis he had several relapses due to several things: weaning him off steroids too soon, reaction to vaccinations and reaction to ivermectin in heartworm medicine.
      He’s been “steroid free” since October 2013 and our routine consists of: 1. Only feeding same dry/wet kibble for meals and treats. Don’t aggravate his digestive system introducing other food types; 2. NO more vaccinations- have Titer test done to keep a check on his immune level: 3. Only Sentinel for Heartworm medicine- as it has no Ivermectin in it; 4. Careful with exposure to bacterial infections that could develop from bodies of water ie ; lakes, streams, rain water on surfaces, etc., 5. Monitor his activity picking up/eating things from the ground that send his system in a whirlwind. And lots of TLC which is easy to do with him. Be glad to continue communication with you on this….if you would like.

  16. Sonya says:

    Our Boxer was diagnosed with MMM and is in the chronic stage. We are trying pred. now but we do not have high hopes unfortunately. We have been going back and forth to the vet for nearly a year but our boy didn’t show the normal signs for the disease. This article helped me a lot with better understanding it. Thank you!

  17. michael says:

    i have a doberman male 3 years old, unfortunately in the country i live in we have no labratory where we can do i biopsy test for mmm.
    all i noticed is that my dog is loosing muscle in his for head at the side and also in his back, there is some sort of hollowness in his back.
    i have been advice to start a course of predisone and anitibiotics but i have no idea on the dosage and length of treatment.
    any help will be grateful.

    • admin says:

      The tests for this are or were sent to the states for confirmation of the condition. And it can take some time. I am not a vet and couldn’t say about dosage your vet would have to do that I’m afraid. My web site is from my own experience and research. I hope it helped you a little. Please soften your dogs food with water as it will be painfull for him to eat. X

  18. emma says:

    We have a Jack Russell terrier who has just been diagnosed with MMM and have been searching to find out more about this. Your article is clearly written and easy to understand – from diagnosis to prognosis I now feel better informed and more at ease. Thank you

    • admin says:

      Thanks Emma, Im Glad you found it of help, i know when our Max had it we couldn’t find any help and it was scary. Hope your pet isn’t too bad. give soft food, like if he is used to kibble soften it with water for an hour before feeding make it easier to chew. wishing you well x

  19. Mick Buldger says:

    Hi there, I check your new stuff on a regular basis.
    Your writing style is witty, keep doing what you’re doing!

  20. Brian McGuinness says:

    Thanks for finally talking about > Masticatory Muscle Myositis | Canine Creche < Liked it!

  21. Max Burns says:

    Howdy! This blog post could not be written much better!
    Looking through this article reminds me of my previous roommate!
    He continually kept preaching about this. I most certainly will
    forward this article to him. Pretty sure he will have a very good
    read. Thank you for sharing!

  22. Ayarza says:

    Perfect work you have done, this website is really cool with great information.

  23. Gerard Roma says:

    It’s really a nice and helpful piece of information.I’m glad that you shared this useful info with us.Please keep us up to date like this.Thanks for sharing

  24. admin says:

    Just thinking about your question, you would think as a lay person that if you are giving treatment for something you are alleviating symptoms and therefore when testing comes along the results will be tainted… but i will look into it …

  25. Gail Noren says:

    If dog is started on prednisone prior to diagnostic testing 2m antibody test), is there a greater likelihood of a false negative?

    • admin says:

      Hi Gail, I will have to try and fond out an answer to that for you as i am not qualified to answer, but i will try to find out for you.

      • Tabitha says:

        I would like to know this as well…..we are considering having our dog checked for this but don’t want meds to disrupt diagnosis….

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